Synchronous oral squamous cell carcinomas with unusual histopathological feature

Synchronous oral paracoccidioidomycosis and oral squamous cell carcinomas with submandibular enlargement.

Oral paracoccidioidomycosis and oral squamous cell carcinoma may occur in the same patient. As both lesions may present similar clinical and histopathological features, the diagnosis is sometimes challenging. This paper describes the case of a 54-year-old male who was a farm worker and heavy alcohol and tobacco user. He developed paracoccidioidomycosis and two lesions of squamous cell carcinoma...

Primary Oral Squamous Cell Carcinomas

Histopathological Patterns of Oral Squamous Cell Carcinoma

The objective of this study was to provide a baseline data on the pattern of oral squamous cell carcinoma in Karachi. The retrospective cross sectional study was conducted. The patients of oral squamous cell carcinoma were examined from January 2007December 2010 at oral maxillofacial department, Darul Sehat Hospital Karachi. All retrievable case files were obtained and necessary data were extra...

Oral squamous cell carcinomas stimulate osteoclast differentiation.

Matrix metalloproteinases (MMPs) play important roles in the invasion and metastasis to soft tissues of carcinomas including, oral squamous cell carcinomas (SCCs). Although, osteoclastic bone resorption is an important step in bone involvement in a variety of malignancies, the mechanism of bone involvement of oral SCC remains unclear. Once cancer cells arrest in bone, the bone is a storehouse o...

Histopathological grading systems analysis of oral squamous cell carcinomas of young patients

BACKGROUND To analyze the clinicopathological profile of young patients (≤ 40 years) with oral SCC and correlate with a control group (≥ 50 years) by means of histopathological grading systems. MATERIAL AND METHODS 14 young patients and 14 control patients were selected with similar clinical stage and tumor location. Demographic and clinical data were obtained from patient records and histolo...